IMPEDIMENTS

\ɪmpˈɛdɪmənts], \ɪmpˈɛdɪmənts], \ɪ_m_p_ˈɛ_d_ɪ_m_ə_n_t_s]\

Definitions of IMPEDIMENTS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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