PIETRO GIORDANI

\pˈa͡ɪ͡ətɹə͡ʊ d͡ʒɪɔːdˈɑːnɪ], \pˈa‍ɪ‍ətɹə‍ʊ d‍ʒɪɔːdˈɑːnɪ], \p_ˈaɪə_t_ɹ_əʊ dʒ_ɪ__ɔː_d_ˈɑː_n_ɪ]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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