PIETROWSKI'S REACTION

\pa͡ɪ͡ətɹˈə͡ʊskɪz ɹɪˈakʃən], \pa‍ɪ‍ətɹˈə‍ʊskɪz ɹɪˈakʃən], \p_aɪə_t_ɹ_ˈəʊ_s_k_ɪ_z ɹ_ɪ__ˈa_k_ʃ_ə_n]\

Definitions of PIETROWSKI'S REACTION

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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