NEURALGIC AMYOTROPHIES
\njuːɹˈald͡ʒɪk ˈamɪˌɒtɹəfɪz], \njuːɹˈaldʒɪk ˈamɪˌɒtɹəfɪz], \n_j_uː_ɹ_ˈa_l_dʒ_ɪ_k ˈa_m_ɪ__ˌɒ_t_ɹ_ə_f_ɪ_z]\
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A syndrome associated with inflammation of the BRACHIAL PLEXUS. Clinical features include severe pain in the shoulder region which may be accompanied by MUSCLE WEAKNESS and loss of sensation in the upper extremity. This condition may be associated with VIRUS DISEASES; IMMUNIZATION; SURGERY; heroin use (see HEROIN DEPENDENCE); and other conditions. The term brachial neuralgia generally refers to pain associated with brachial plexus injury. (From Adams et al., Principles of Neurology, 6th ed, pp1355-6)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.