HYPOSPADIA
\hˌa͡ɪpə͡ʊspˈe͡ɪdiə], \hˌaɪpəʊspˈeɪdiə], \h_ˌaɪ_p_əʊ_s_p_ˈeɪ_d_i__ə]\
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A developmental anomaly in the male in which the urethra opens on the underside of the penis or on the perineum.
By DataStellar Co., Ltd
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A malformation, in which the canal of the urethra, instead of opening at the apex of the glans, terminates at its base, or beneath the penis, at a greater or less distance from the symphysis pubis. When the orifice of the urethra is very near the root of the penis, the scrotum is divided, as it were, into two great labia; and this malformation has often been taken for a case of hermaphrodism. Hypospadia is ordinarily incurable; and an idea has been entertained that it is the cause of impotence. It is not exactly so; but it renders impregnation less probable.
By Robley Dunglison
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.