WYLIE-COAT

\wˈa͡ɪlikˈə͡ʊt], \wˈa‍ɪlikˈə‍ʊt], \w_ˈaɪ_l_i_k_ˈəʊ_t]\
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1899 - The american dictionary of the english language.
By Daniel Lyons
 
1908 - Chambers's Twentieth Century Dictionary of the English Language
By Thomas Davidson

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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