RATCHET EFFECT
\ɹˈat͡ʃɪt ɪfˈɛkt], \ɹˈatʃɪt ɪfˈɛkt], \ɹ_ˈa_tʃ_ɪ_t ɪ_f_ˈɛ_k_t]\
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.