GAINSAYER

\ɡˈe͡ɪnse͡ɪə], \ɡˈe‍ɪnse‍ɪə], \ɡ_ˈeɪ_n_s_eɪ_ə]\
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  • n. One who gainsays, contradicts, or denies; an opposer.
1871 - The Cabinet Dictionary of the English Language
 
1790 - A Complete Dictionary of the English Language
By Thomas Sheridan

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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