EXCESSIVE SOMNOLENCE DISORDER
\ɛksˈɛsɪv sˈɒmnələns dɪsˈɔːdə], \ɛksˈɛsɪv sˈɒmnələns dɪsˈɔːdə], \ɛ_k_s_ˈɛ_s_ɪ_v s_ˈɒ_m_n_ə_l_ə_n_s d_ɪ_s_ˈɔː_d_ə]\
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Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153 (2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.