EXCESSIVE PERIODIC SLEEP RELATED LEG MOVEMENTS
\ɛksˈɛsɪv pˌi͡əɹɪˈɒdɪk slˈiːp ɹɪlˈe͡ɪtɪd lˈɛɡ mˈuːvmənts], \ɛksˈɛsɪv pˌiəɹɪˈɒdɪk slˈiːp ɹɪlˈeɪtɪd lˈɛɡ mˈuːvmənts], \ɛ_k_s_ˈɛ_s_ɪ_v p_ˌiə_ɹ_ɪ__ˈɒ_d_ɪ_k s_l_ˈiː_p ɹ_ɪ_l_ˈeɪ_t_ɪ_d l_ˈɛ_ɡ m_ˈuː_v_m_ə_n_t_s]\
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Excessive periodic leg movements during sleep that cause micro-arousals and interfere with the maintenance of sleep. This condition induces a state of relative sleep deprivation which manifests as excessive daytime hypersomnolence. The movements are characterized by repetitive contractions of the tibialis anterior muscle, extension of the toe, and intermittent flexion of the hip, knee and ankle. (Adams et al., Principles of Neurology, 6th ed, p387)
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Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
Nearby Words
- excerpts
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- Excessive Periodic Sleep Related Leg Movements
- excessive somnolence disorder
- excessive somnolence disorders
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- excessively