UNCOUPLING AGENTS
\ʌnkˈʌplɪŋ ˈe͡ɪd͡ʒənts], \ʌnkˈʌplɪŋ ˈeɪdʒənts], \ʌ_n_k_ˈʌ_p_l_ɪ_ŋ ˈeɪ_dʒ_ə_n_t_s]\
Sort: Oldest first
-
Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.