STATUS CATAPLEXICUS
\stˈe͡ɪtəs kˌatɐplˈɛksɪkəs], \stˈeɪtəs kˌatɐplˈɛksɪkəs], \s_t_ˈeɪ_t_ə_s k_ˌa_t_ɐ_p_l_ˈɛ_k_s_ɪ_k_ə_s]\
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A condition characterized by transient weakness or paralysis of somatic musculature triggered by an emotional stimulus or physical exertion. Cataplexy is frequently associated with NARCOLEPSY. During a cataleptic attack, there is a marked reduction in muscle tone similar to the normal physiologic hypotonia that accompanies rapid eye movement sleep (SLEEP, REM). (From Adams et al., Principles of Neurology, 6th ed, p396)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.