RESTITUTIO AD INTEGRUM

\ɹɪstɪtjˈuːtɪˌə͡ʊ ˈad ˈɪntɛɡɹəm], \ɹɪstɪtjˈuːtɪˌə‍ʊ ˈad ˈɪntɛɡɹəm], \ɹ_ɪ_s_t_ɪ_t_j_ˈuː_t_ɪ__ˌəʊ ˈa_d ˈɪ_n_t_ɛ_ɡ_ɹ_ə_m]\

Definitions of RESTITUTIO AD INTEGRUM

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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