NEGATIVE AMORTIZATION

\nˈɛɡətˌɪv ɐmˌɔːta͡ɪzˈe͡ɪʃən], \nˈɛɡətˌɪv ɐmˌɔːta‍ɪzˈe‍ɪʃən], \n_ˈɛ_ɡ_ə_t_ˌɪ_v ɐ_m_ˌɔː_t_aɪ_z_ˈeɪ_ʃ_ə_n]\
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2010 - Legal Glossary Database
By Oddity Software
 
1910 - Black's Law Dictionary (2nd edition)
By Henry Campbell Black

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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