MANICHæAN

\mˈanɪʃ ˌe͡ɪtˈɪldə ɐn], \mˈanɪʃ ˌe‍ɪtˈɪldə ɐn], \m_ˈa_n_ɪ_ʃ ˌeɪ__t_ˈɪ_l_d_ə_ ɐ_n]\
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1908 - Chambers's Twentieth Century Dictionary of the English Language
By Thomas Davidson

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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