EXTRA ADRENAL PARAGANGLIOMAS
\ˈɛkstɹəɹ ɐdɹˈiːnə͡l pˌaɹəɡˌaŋɡlɪˈə͡ʊməz], \ˈɛkstɹəɹ ɐdɹˈiːnəl pˌaɹəɡˌaŋɡlɪˈəʊməz], \ˈɛ_k_s_t_ɹ_ə_ɹ ɐ_d_ɹ_ˈiː_n_əl p_ˌa_ɹ_ə_ɡ_ˌa_ŋ_ɡ_l_ɪ__ˈəʊ_m_ə_z]\
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A relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the carotid body, glomus jugulare, and aortic bodies. It consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. They are uncommon before the age of 20, with a female predominance in some series. (Stedman, 25th ed; from DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p570-1)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
Nearby Words
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