YCLEPT
\ˈɪklɛpt], \ˈɪklɛpt], \ˈɪ_k_l_ɛ_p_t]\
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By James Champlin Fernald
By Thomas Davidson
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.