WHETSTONE-SLATE

\wˈɛtstə͡ʊnslˈe͡ɪt], \wˈɛtstə‍ʊnslˈe‍ɪt], \w_ˈɛ_t_s_t_əʊ_n_s_l_ˈeɪ_t]\

Definitions of WHETSTONE-SLATE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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