STAY IN PLACE
\stˈe͡ɪ ɪn plˈe͡ɪs], \stˈeɪ ɪn plˈeɪs], \s_t_ˈeɪ ɪ_n p_l_ˈeɪ_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.