SNEDDON CHAMPION SYNDROME
\snˈɛdən t͡ʃˈampi͡ən sˈɪndɹə͡ʊm], \snˈɛdən tʃˈampiən sˈɪndɹəʊm], \s_n_ˈɛ_d_ə_n tʃ_ˈa_m_p_iə_n s_ˈɪ_n_d_ɹ_əʊ_m]\
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A systemic non-inflammatory arteriopathy primarily of middle-aged females characterized by the association of livedo reticularis, multiple thrombotic CEREBRAL INFARCTION; CORONARY DISEASE, and HYPERTENSION. Elevation of antiphospholipid antibody titers (see also ANTIPHOSPHOLIPID SYNDROME), cardiac valvulopathy, ISCHEMIC ATTACK, TRANSIENT; SEIZURES; DEMENTIA; and chronic ischemia of the extremities may also occur. Pathologic examination of affected arteries reveals non-inflammatory adventitial fibrosis, thrombosis, and changes in the media. (From Jablonski, Dictionary of Syndromes & Eponymic Diseases, 2d ed; Adams et al., Principles of Neurology, 6th ed, p861; Arch Neurol 1997 Jan;54 (1):53-60)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
Nearby Words
- sneathe
- sneb
- sneck
- snecket
- sned
- Sneddon Champion Syndrome
- sneddon syndrome
- sneddon wilkinson disease
- snee
- sneed
- sneer