LEO AFRICANUS

\lˈiːə͡ʊ ˈafɹɪkˌanəs], \lˈiːə‍ʊ ˈafɹɪkˌanəs], \l_ˈiː__əʊ ˈa_f_ɹ_ɪ_k_ˌa_n_ə_s]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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