ICI66082

\ˈa͡ɪsa͡ɪ sˈɪkstisˈɪks θˈa͡ʊzənd ən ˈe͡ɪtitˈuː], \ˈa‍ɪsa‍ɪ sˈɪkstisˈɪks θˈa‍ʊzənd ən ˈe‍ɪtitˈuː], \ˈaɪ_s_aɪ s_ˈɪ_k_s_t_i_s_ˈɪ_k_s θ_ˈaʊ_z_ə_n_d_ ə_n ˈeɪ_t_i_t_ˈuː]\

Definitions of ICI66082

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2010 - Medical Dictionary Database
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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