HOLTZ MACHINE

\hˈə͡ʊltz məʃˈiːn], \hˈə‍ʊltz məʃˈiːn], \h_ˈəʊ_l_t_z m_ə_ʃ_ˈiː_n]\

Definitions of HOLTZ MACHINE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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