HAEMOMEDIASTINUM

\hˌiːmə͡ʊmˈiːdɪˌastɪnəm], \hˌiːmə‍ʊmˈiːdɪˌastɪnəm], \h_ˌiː_m_əʊ_m_ˈiː_d_ɪ__ˌa_s_t_ɪ_n_ə_m]\
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1900 - A dictionary of medicine and the allied sciences
By Alexander Duane

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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