HAB-EL-KALIMBAT
\hˈabˌɛlkˈalɪmbˌat], \hˈabˌɛlkˈalɪmbˌat], \h_ˈa_b_ˌɛ_l_k_ˈa_l_ɪ_m_b_ˌa_t]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.