BIG APPLE
\bˈɪɡ ˈapə͡l], \bˈɪɡ ˈapəl], \b_ˈɪ_ɡ ˈa_p_əl]\
Definitions of BIG APPLE
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.