AWAKENING EPILEPSY
\ɐwˈe͡ɪknɪŋ ˈɛpɪlˌɛpsi], \ɐwˈeɪknɪŋ ˈɛpɪlˌɛpsi], \ɐ_w_ˈeɪ_k__n_ɪ_ŋ ˈɛ_p_ɪ_l_ˌɛ_p_s_i]\
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A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.