YEAST ARTIFICIAL CHROMOSOMES
\jˈiːst ˌɑːtɪfˈɪʃə͡l kɹˈə͡ʊməsˌə͡ʊmz], \jˈiːst ˌɑːtɪfˈɪʃəl kɹˈəʊməsˌəʊmz], \j_ˈiː_s_t ˌɑː_t_ɪ_f_ˈɪ_ʃ_əl k_ɹ_ˈəʊ_m_ə_s_ˌəʊ_m_z]\
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Chromosomes in which fragments of exogenous DNA ranging in length up to several hundred kilobase pairs have been cloned into yeast through ligation to vector sequences. These artificial chromosomes are used extensively in molecular biology for the construction of comprehensive genomic libraries of higher organisms.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
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