WILLIS CIRCLE

\wˈɪlis sˈɜːkə͡l], \wˈɪlis sˈɜːkə‍l], \w_ˈɪ_l_i_s s_ˈɜː_k_əl]\

Definitions of WILLIS CIRCLE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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