WEIR-MITCHELL'S DISEASE

\wˈi͡əmˈɪt͡ʃə͡lz dɪzˈiːz], \wˈi‍əmˈɪt‍ʃə‍lz dɪzˈiːz], \w_ˈiə_m_ˈɪ_tʃ_əl_z d_ɪ_z_ˈiː_z]\

Definitions of WEIR-MITCHELL'S DISEASE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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