VACUOLATING AGENT

\vˈakjuːˌɒle͡ɪtɪŋ ˈe͡ɪd͡ʒənt], \vˈakjuːˌɒle‍ɪtɪŋ ˈe‍ɪd‍ʒənt], \v_ˈa_k_j_uː_ˌɒ_l_eɪ_t_ɪ_ŋ ˈeɪ_dʒ_ə_n_t]\

Definitions of VACUOLATING AGENT

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2010 - Medical Dictionary Database
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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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