UPREGULATION
\ˌʌpɹɪɡjuːlˈe͡ɪʃən], \ˌʌpɹɪɡjuːlˈeɪʃən], \ˌʌ_p_ɹ_ɪ_ɡ_j_uː_l_ˈeɪ_ʃ_ə_n]\
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A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrance receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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