UNCOUNSELLED
\ʌnkˈa͡ʊnsə͡ld], \ʌnkˈaʊnsəld], \ʌ_n_k_ˈaʊ_n_s_əl_d]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.