TAC PEPTIDE
\tˈak pˈɛpta͡ɪd], \tˈak pˈɛptaɪd], \t_ˈa_k p_ˈɛ_p_t_aɪ_d]\
Sort: Oldest first
-
Receptors present on activated T- and B-cells as a complex consisting of a 55 kD peptide, which reacts with the anti-Tac monoclonal antibody, and a 75 kD non-Tac interleukin-2-binding peptide. The receptor is present in two forms, one with a very high affinity and the other with low affinity for IL-2. The high-affinity form appears to mediate exclusively the growth-promoting response to IL-2. The receptor is present in large numbers on resting HUMAN T-LYMPHOTROPIC VIRUS 1 leukemia cells, but not on normal resting cells.
By DataStellar Co., Ltd
