SYNDETICON

\sˈɪndɪtˌɪkən], \sˈɪndɪtˌɪkən], \s_ˈɪ_n_d_ɪ_t_ˌɪ_k_ə_n]\

Definitions of SYNDETICON

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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