STUNNED MYOCARDIUM
\stˈʌnd mˌa͡ɪəkˈɑːdi͡əm], \stˈʌnd mˌaɪəkˈɑːdiəm], \s_t_ˈʌ_n_d m_ˌaɪ_ə_k_ˈɑː_d_iə_m]\
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Prolonged dysfunction of the myocardium after a brief episode of severe ischemia, with gradual return of contractile activity. It occurs frequently, both in the experimental laboratory and in clinical medicine. Since stunned myocardium occurs adjacent to necrotic tissue after prolonged coronary occlusion, many myocardial infarcts may be a mixture of necrotic and stunned tissue. (Braunwald, Heart Disease, 1992, p1176)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.