SANGER'S MACULA

\sˈaŋɡəz mˈakjʊlə], \sˈaŋɡəz mˈakjʊlə], \s_ˈa_ŋ_ɡ_ə_z m_ˈa_k_j_ʊ_l_ə]\

Definitions of SANGER'S MACULA

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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