PAPULA
\pˈapjʊlə], \pˈapjʊlə], \p_ˈa_p_j_ʊ_l_ə]\
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A small, acuminated elevation of the cuticle, with an inflamed base; very seldom containing a fluid, or suppurating, and commonly terminating in scurf or desquamation. An eruption of pimples is called, in Devonshire, Murfles. Papulae form the first order of Willan and Bateman’s arrangement of cutaneous diseases.
By Robley Dunglison
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.