NEUROBORRELIOSES, BORRELIA BURGDORFERI
\njˈuːɹəbˌɒɹɪlɪˌə͡ʊzɪz], \njˈuːɹəbˌɒɹɪlɪˌəʊzɪz], \n_j_ˈuː_ɹ_ə_b_ˌɒ_ɹ_ɪ_l_ɪ__ˌəʊ_z_ɪ_z]\
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Nervous system infections caused by tick-borne spirochetes of the BORELLIA BORGDORFERI GROUP. The disease may affect elements of the central or peripheral nervous system in isolation or in combination. Common clinical manifestations include a lymphocytic meningitis, cranial neuropathy (most often a facial neuropathy), POLYRADICULOPATHY, and a mild loss of memory and other cognitive functions. Less often more extensive inflammation involving the central nervous system (encephalomyelitis) may occur. In the peripheral nervous system, B. burgdorferi infection is associated with mononeuritis multiplex and polyradiculoneuritis. (From J Neurol Sci 1998 Jan 8;153 (2):182-91)
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Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
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