NEGOTIATOR

\nɪɡˈə͡ʊʃɪˌe͡ɪtə], \nɪɡˈə‍ʊʃɪˌe‍ɪtə], \n_ɪ_ɡ_ˈəʊ_ʃ_ɪ__ˌeɪ_t_ə]\

Definitions of NEGOTIATOR

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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