MITOMYCIN C
\mˈa͡ɪtəmˌɪsɪn sˈiː], \mˈaɪtəmˌɪsɪn sˈiː], \m_ˈaɪ_t_ə_m_ˌɪ_s_ɪ_n s_ˈiː]\
Sort: Oldest first
-
An antineoplastic antibiotic produced by Streptomyces caespitosus. It acts as a bi- or trifunctional alkylating agent causing cross-linking of DNA and inhibition of DNA synthesis.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.