MAJOR HISTOCOMPATIBILITY COMPLEX
\mˈe͡ɪd͡ʒə hˌɪstəkˌɒmpɐtɪbˈɪlɪti kˈɒmplɛks], \mˈeɪdʒə hˌɪstəkˌɒmpɐtɪbˈɪlɪti kˈɒmplɛks], \m_ˈeɪ_dʒ_ə h_ˌɪ_s_t_ə_k_ˌɒ_m_p_ɐ_t_ɪ_b_ˈɪ_l_ɪ_t_i k_ˈɒ_m_p_l_ɛ_k_s]\
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The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD) transplantation antigens, genes which control the structure of the immune response-associated (Ia) antigens, the immune response (Ir) genes which control the ability of an animal to respond immunologically to antigenic stimuli, and genes which determine the structure and/or level of the first four components of complement.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.