LASERPITIUM SILER

\lˌazəpˈɪti͡əm sˈa͡ɪlə], \lˌazəpˈɪti‍əm sˈa‍ɪlə], \l_ˌa_z_ə_p_ˈɪ_t_iə_m s_ˈaɪ_l_ə]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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