LACUNAE OF BONE

\lˈakənˌiː ɒv bˈə͡ʊn], \lˈakənˌiː ɒv bˈə‍ʊn], \l_ˈa_k_ə_n_ˌiː_ ɒ_v b_ˈəʊ_n]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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