ITARD-CHOLEWA SIGN

\ˈɪtɑːdkˈə͡ʊlwə sˈa͡ɪn], \ˈɪtɑːdkˈə‍ʊlwə sˈa‍ɪn], \ˈɪ_t_ɑː_d_k_ˈəʊ_l_w_ə s_ˈaɪ_n]\

Definitions of ITARD-CHOLEWA SIGN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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