HYPOTHALAMUS NEOPLASMS
\hˌa͡ɪpə͡ʊθˈalaməs nˈiːə͡ʊplˌazəmz], \hˌaɪpəʊθˈalaməs nˈiːəʊplˌazəmz], \h_ˌaɪ_p_əʊ_θ_ˈa_l_a_m_ə_s n_ˈiː__əʊ_p_l_ˌa_z_ə_m_z]\
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Benign and malignant tumors of the HYPOTHALAMUS. Pilocytic astrocytomas and hamartomas are relatively frequent histologic types. Neoplasms of the hypothalamus frequently originate from adjacent structures, including the OPTIC CHIASM, optic nerve (see OPTIC NERVE NEOPLASMS), and pituitary gland (see PITUITARY NEOPLASMS). Relatively frequent clinical manifestions include visual loss, developmental delay, macrocephaly, and precocious puberty. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2051)
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Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.