HAMBERGER’S ACHEMA

\hˈambəd͡ʒəz ˈe͡ɪkmə], \hˈambəd‍ʒəz ˈe‍ɪkmə], \h_ˈa_m_b_ə_dʒ_ə_z ˈeɪ_k_m_ə]\

Definitions of HAMBERGER’S ACHEMA

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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