GASTRIN PRODUCING TUMORS
\ɡˈastɹɪn pɹədjˈuːsɪŋ tjˈuːməz], \ɡˈastɹɪn pɹədjˈuːsɪŋ tjˈuːməz], \ɡ_ˈa_s_t_ɹ_ɪ_n p_ɹ_ə_d_j_ˈuː_s_ɪ_ŋ t_j_ˈuː_m_ə_z]\
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A gastrin-secreting tumor of the non-beta islet cells. It is usually located in the pancreas but is also found at other sites, as in the antrum of the stomach, hilus of the spleen, and regional lymph nodes. The presence of gastrinoma is one of three requirements to be met for identification of ZOLLINGER-ELLISON SYNDROME, which sometimes occurs in families with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; (MEN-1). Gastrinomas in patients with MEN-1 are usually diffuse in nature.
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