FIBRINOGEN
\fˈɪbɹɪnəd͡ʒən], \fˈɪbɹɪnədʒən], \f_ˈɪ_b_ɹ_ɪ_n_ə_dʒ_ə_n]\
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Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
By DataStellar Co., Ltd
By William R. Warner
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A soluble constituent of blood which yields fibrin and produces coagulation.
By Henderson, I. F.; Henderson, W. D.
By Willam Alexander Newman Dorland
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.