CHAUFFARD'S SYNDROME
\ʃˈə͡ʊfədz sˈɪndɹə͡ʊm], \ʃˈəʊfədz sˈɪndɹəʊm], \ʃ_ˈəʊ_f_ə_d_z s_ˈɪ_n_d_ɹ_əʊ_m]\
Definitions of CHAUFFARD'S SYNDROME
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.